In the contemporary landscape of urban development, sustainable practices have emerged as a crucial element for creating modern, active, and resilient cities. The “Sustainable Bio-climatic Revitalization of Abandoned Urban Space” project underscores the importance of adopting a multidisciplinary approach. By analyzing various aspects related to the environment and climate change, the project aims to provide innovative solutions that serve as exemplars for the sustainable rejuvenation of abandoned spaces, particularly those with cultural heritage significance.